Although current trials have demonstrated that intensive glucose management may be harmful in comparison with less-intensive normal treatment in older sufferers with advanced type 2 diabetes 7 , 8 , tight glycemic management was related to slowed development of retinopathy 9 , 10 and may particularly scale back the chance of micro- and macrovascular illness when started earlier in the disease course 11 The ingestion of protein with glucose has been shown to enhance insulin secretion and diminish the plasma glucose response in persons with type 2 diabetes 12 It has been recently reported that lysine (a readily abundant important amino acid), when ingested with glucose, facilitates a discount within the glucose space beneath the curve (AUC) by 44% with none change in plasma insulin, along with a discount in plasma glucagon thirteen Thus, lysine supplementation could signify a novel and cost-effective therapeutic intervention to scale back hyperglycemia and associated CVD outcomes with out potential issues associated with different nutritional, behavioral, or pharmacological interventions.
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